Revolutionary nanosensor: diagnosing lung cancer using exhalation becomes a reality
An innovative breakthrough by Chinese scientists: a highly sensitive nanosensor has been created that can diagnose lung cancer by analyzing the concentration of isoprene in exhaled air, opening up new opportunities for early and non-invasive diagnosis of the disease.
Nanosensor against cancer
Revolutionary development
Experts from China have created an innovative nanosensor that allows one to determine the presence of lung cancer by the concentration of isoprene in the patient’s breath. This invention opens up prospects for creating an accessible and non-invasive method for early diagnosis of oncology.
Mechanism of action
In the process of lipolytic metabolism of cholesterol, the human body releases isoprene through the respiratory tract. A Zhejiang University research team found that low levels of this substance may indicate lung cancer. Based on this discovery, a special gas-sensitive material for screening was developed.
Technical features
A key challenge in identifying biomarkers in exhaled air is the need to create sensors capable of distinguishing volatile compounds at high exhaled humidity and determine the minimum concentrations of substances. Isoprene requires sensors with ppb (parts per billion) sensitivity.
Test results
The developed Pt@InNiOx material showed exceptional sensitivity, detecting isoprene concentrations as low as two ppb. In testing on 13 volunteers, including five lung cancer patients, the sensor detected isoprene levels below 40 ppb in patients and above 60 ppb in healthy participants.
Prospects for use
According to statistics WHO, in 2020 Lung cancer claimed 1.8 million lives this year. The publication of in ACS Sensors demonstrates the potential of the new diagnostic method, although more research is required to commercialize it.
Glossary
- Pt@InNiOx - an innovative nanomaterial for detecting isoprene in exhaled air
- Zhejiang University - China's leading research university
- WHO - World Health Organization
- ACS Sensors - scientific journal of the American Chemical Society
- Cancer Research UK - leading cancer research charity
Links
- WHO statistics on lung cancer
- Research publication in ACS Sensors
- Cancer diagnostic studies using exhaled air
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Discussion of the topic – Revolutionary nanosensor: diagnosing lung cancer using exhalation becomes a reality
Chinese scientists have created an innovative nanosensor capable of detecting lung cancer by analyzing isoprene in exhaled air. The technology promises to become an affordable and non-invasive method of early diagnosis.
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Giovanni
Incredible! This simple diagnostic method could save millions of lives. 1.8 million deaths is a terrifying statistic. Imagine, I just exhaled - and you already know the diagnosis 🤯
Marie
My aunt died of lung cancer, it was discovered too late. If only such technology existed before... I hope Chinese scientists will speed up the implementation of this method into practice 😔
Klaus
As a biochemist, I can say that the technology is promising. Determination of biomarkers in exhaled air is the future of diagnostics. The main advantage is non-invasiveness and simplicity 🔬
Herbert
Again these fashionable stories about nanotechnology. I’ve been hearing about breakthroughs for 20 years now, but what’s the point? Everyone still goes for a biopsy and CT scan. I don’t believe in these fairy tales about exhaling and you’re done 🙄
Isabella
Herbert, but technology does not stand still! Look at the progress in medicine in recent years. And the possibility of mass screening will save many lives 💪
Klaus
Exactly! There are already successful tests at the ppb level. Isabella is right - this is a revolution in oncology diagnostics 🔋
Marie
Giovanni, I agree! The simplicity of the method will allow for mass examinations. Imagine - I went into the clinic, exhaled and immediately the result 👨⚕️
Giovanni
Klaus, how accurate are such tests? Will there be any false positives? 🤔